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Research Reveals Gene Expression Alterations Can Trigger Autism

Research Reveals Gene Expression Alterations Can Trigger Autism
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Japan General , Takaoki Kasahara , Atsushi Takata , Takumi Nakamura , Kurara Honda , Junko Ueda , Toru Takumi , Masahide Asano , Moe Nakanishi , Shigeyoshi Itohara , Tomonori Hara , Tadafumi Kato , Mitsutaka Kadota , Chiharu Tanegashima , Takashi Tsuboi , Shigehiro Kuraku , Yuki Kobayashi , Mizuho Ishiwata , Kazuo Nakajima , Toru Yoshihara , Kyoto University Graduate School Of Medicine , Laboratory For Behavioral Genetics , Department Of Life Sciences , Society Of Biological Psychiatry Academic Award , Carl Von Ossietzky University Of Oldenburg , Teikyo University School Of Medicine ,

New study uncovers how altered gene expressio

<p><strong>The loss-of-function mutation of <em>KMT2C</em>, a gene involved in histone modification, leads to the development of autism and other neurodevelopmental deficits. However, the precise mechanism of the disease progression is still unknown. Now, researchers from Japan have developed an animal model and elucidated the mechanism by which mutation in genes involved in chromatin modification causes autism. They have also discovered a drug that can be used in the treatment of autism.</strong></p>
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Japan General , Shigehiro Kuraku , Tadafumi Kato , Kurara Honda , Takumi Nakamura , Atsushi Takata , Junko Ueda , Takashi Tsuboi , Mizuho Ishiwata , Toru Takumi , Tomonori Hara , Shigeyoshi Itohara , Toru Yoshihara , Takaoki Kasahara , Chiharu Tanegashima , Yuki Kobayashi , Masahide Asano , Sumitomo Dainippon Pharma , Moe Nakanishi , Mitsutaka Kadota , Kazuo Nakajima , Teikyo University School Of Medicine , Research Institute For Diseases Of Old Age , Carl Von Ossietzky University Of Oldenburg , Department Of Genetics , Laboratory For Behavioral Genetics ,

New study uncovers how altered gene expressio

New study uncovers how altered gene expressio
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Japan General , Takumi Nakamura , Shigehiro Kuraku , Kurara Honda , Tadafumi Kato , Tomonori Hara , Atsushi Takata , Sumitomo Dainippon Pharma , Takaoki Kasahara , Moe Nakanishi , Toru Takumi , Toru Yoshihara , Yuki Kobayashi , Shigeyoshi Itohara , Mizuho Ishiwata , Takashi Tsuboi , Kazuo Nakajima , Masahide Asano , Chiharu Tanegashima , Junko Ueda , Mitsutaka Kadota , Laboratory For Mental Biology , Method Of Research , Kyushu University , Tohoku University Graduate School Of Medicine , Department Of Physiology ,

Shockable impact on heart

Shockable impact on heart
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Yohei Okada , Kyoto University Graduate School Of Medicine , Kyoto University , Graduate School ,

The Sweet Achilles' Heel of Cancer: Sugar Chains As the Key to Advanced Immunotherapy

Research shows B4GALT3 deficiency in mice slows tumor growth and alters immune responses, suggesting new cancer treatment strategies. An old campaign slogan for cough syrup, "It tastes awful. And it works," seemed to imply that any sweet content might have diminished the medicinal effect. The Ro ....

Japan General , Cheng Wei , Saki Ikeda , Xuchi Pan , Masahide Asano , Kazushi Sugihara , Daisuke Takakura , Kyoto University Graduate School Of Medicine , Kyoto University , Yokohama City University , Cancer Genome Atlas , Sweet Achilles Heel , Kyotou Jake , Graduate School , Chie Naruse , Nana Kawasaki ,