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Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the brain for treating neurological conditions like Alzheimer's disease is challenging as they are either cleared out of the blood very quickly or do not penetrate neural tissue effectively. ....

Kunio Matsumoto , Hiroaki Suga , Emily Henderson , University Of Tokyo , Lab Diagnostics Automation , Lab Diagnostics Automation Industry , Junichi Takagi At Osaka University , Katsuya Sakai At Kanazawa University , Junichi Takagi , Osaka University , Katsuya Sakai , Kanazawa University , Automation Industry Focus , Drug Delivery , Lzheimer 39s Disease ,

Biological lasso: Enhanced drug delivery to the brain

Biological lasso: Enhanced drug delivery to the brain
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Ryu Imamura , Mikihiro Shibata , Katsuya Sakai , Hiroaki Suga , Chihiro Yamasaki , Dominic Chih Cheng Voon , Emiko Mihara , Nozomi Sugano Nakamura , Kunio Matsumoto , Itsuki Sakai , Hiroki Sato , Junichi Takagi , Sayako Watanabe , Osaka University , University Of Tokyo , Katsuya Sakai At Kanazawa University , Kanazawa University , Chise Tateno ,