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Future vaccines depend on primate test subjects in short supply

A global monkey shortage, resulting from the unexpected demand caused by the pandemic, has been exacerbated by a recent ban on the sale of wildlife from China. ....

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Future Vaccines Depend on Test Subjects in Short Supply: Monkeys

Future Vaccines Depend on Test Subjects in Short Supply: Monkeys
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The Hindu Explains | What has the WHO team's field visit to China thrown up regarding the spread of SARS-CoV-2?

Updated:
February 14, 2021 13:18 IST
Has the possibility of a lab-leak been ruled out? Did the virus directly jump from bats to humans?
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Has the possibility of a lab-leak been ruled out? Did the virus directly jump from bats to humans?
The story so far: After several months of delay, concerns over access, and bickering between China and the U.S., a 17-member team from the World Health Organisation began a field visit on January 29, 2021, to unearth the origin of the SARS-CoV-2 virus that has so far spread to over 108 million people and killed nearly 2.4 million people across the globe. According to the WHO, the field visits included the Wuhan Institute of Virology, the Huanan market, and the Wuhan CDC (Center for Disease Control and Prevention) laboratory. It said the team was “limited to visits organised by Chinese hosts and had no contact with community members, because of health restrictions”, Reuters reported. ....

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Rhesus macaques develop promising immune response to SARS-CoV-2

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In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine. The work was carried out at the California National Primate Research Center at the University of California, Davis and is published Jan. 22 in the journal
Nature Communications.
These results suggest that vaccines inducing durable protective immunity against SARS-CoV-2 do so by stimulating robust germinal center responses - a question that can be effectively answered using the rhesus model, said Smita Iyer, assistant professor of pathology, microbiology and immunology at the UC Davis School of Veterinary Medicine and Center for Immunology and Infectious Diseases. ....

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Zika Virus Affects Fetal Eye Development During Pregnancy but Not After Birth

Zika Virus Affects Fetal Eye Development During Pregnancy but Not After Birth
by Iswarya on
December 21, 2020 at 12:33 PM
Zika infection during the first trimester of pregnancy can affect fetal retinal development and cause congenital ocular anomalies; however, the virus does not appear to affect ocular growth postnatally, according to a new study. The findings of the study are published in the journal
JCI Insight.
While the SARS-CoV-2 virus has dominated the news this past year, researchers continue to study the health effects of the Zika virus, which has been reported in 86 countries globally.
The Zika virus is primarily transmitted by the bite of an infected mosquito from the Aedes genus. However, it can also be passed through sexual contact, blood transfusions, organ transplants, and between mother and baby during pregnancy. The virus has been documented to cause a range of birth defects, including microcephaly and various neurolo ....

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