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Merkel cell carcinoma: Causes, symptoms, and treatment Merkel cell carcinoma is a rare, aggressive type of skin cancer. Merkel cell carcinoma (MCC) gets its name because these skin cancer cells resemble Merkel cells, which are located in the top layer of skin. Merkel cells are most concentrated in the fingertips, lips, and face, but MCC cells are most likely to develop on the head, neck, and other areas that have received the most sun exposure. Below, learn about the causes of MCC, its symptoms, and how to prevent it. We also describe the diagnosis and treatment options. What is MCC? ....