Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.
Brain neurons re-entering the cell cycle age quickly and shift to senescence, particularly in neurodegenerative disease medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.
Wake Up, Age Fast: Brain Neurons Swiftly Shift to Senescence miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Summary: The neurons of patients with Alzheimer's disease tend to reenter the cell cycle and progress rapidly toward senescence. Using advanced snRNA-seq