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Study highlights glycolysis as a potential therapeutic target to combat Mycobacterium tuberculosis

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism -; the intrinsic link between metabolism in immune cells and their immune function. ....

Kwazulu Natal , South Africa , Michael Niederweis , Krishnac Chinta , Anupam Agarwal , Joeln Glasgow , Kapongo Lumamba , Adrie Steyn , Riteshr Sevalkar , Haydent Pacl , Threnesan Naidoo , Vineelp Reddy , Kievershen Nargan , Sajid Nadeem , University Of Kwazulu Natal , University Of Alabama , World Health Organization , Division Of Nephrology , Walter Sisulu University , National Institutes Of Health , Nature Communications , University Of Alabama At Birmingham , Department Of Microbiology , Department Of Medicine , Africa Health Research Institute , World Health ,

Potential therapeutic target found to combat tuberculosis, a disrupted NAD(H) homeostasis

Tuberculosis, the world’s leading infectious disease killer, caused 1.6 million deaths in 2021, along with 10 million new cases of tuberculosis every year. Tuberculosis, the world’s leading infectious disease killer, cau. ....

Kwazulu Natal , South Africa , New Haven , United States , Joeln Glasgow , Michael Niederweis , Threnesan Naidoo , Adrie Steyn , Anupam Agarwal , Vineelp Reddy , Kievershen Nargan , Riteshr Sevalkar , Kapongo Lumamba , Haydent Pacl , Sajid Nadeem , Krishnac Chinta , Walter Sisulu University , Physician Scientist Training Program , World Health Organization , Nature Communications , Marnixe Heersink School Of Medicine , National Institutes Of Health , University Of Alabama , Department Of Medicine , Africa Health Research Institute , Department Of Microbiology ,

Research highlights disrupted NAD(H) homeostasis as a potential therapeutic target to combat tuberculosis

Research highlights disrupted NAD(H) homeostasis as a potential therapeutic target to combat tuberculosis
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Kwazulu Natal , South Africa , Vineelp Reddy , Haydent Pacl , Michael Niederweis , Adrie Steyn , Threnesan Naidoo , Riteshr Sevalkar , Krishnac Chinta , Anupam Agarwal , Joeln Glasgow , Kapongo Lumamba , Kievershen Nargan , Sajid Nadeem , University Of Alabama , World Health Organization , Nature Communications , Department Of Microbiology , Africa Health Research Institute , Department Of Medicine , Division Of Nephrology , University Of Kwazulu Natal , Walter Sisulu University , World Health , Eastern Cape ,

Target Discovered to Battle Tuberculosis via NAD

Target Discovered to Battle Tuberculosis via NAD
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Kwazulu Natal , South Africa , New Haven , United States , Threnesan Naidoo , Vineelp Reddy , Kievershen Nargan , Michael Niederweis , Riteshr Sevalkar , Kapongo Lumamba , Adrie Steyn , Sajid Nadeem , Joeln Glasgow , Krishnac Chinta , Anupam Agarwal , Haydent Pacl , Physician Scientist Training Program , Walter Sisulu University , World Health Organization , Africa Health Research Institute , Marnixe Heersink School Of Medicine , University Of Kwazulu Natal , Scientist Training Program , Department Of Medicine , Division Of Nephrology , Department Of Microbiology ,

Tuberculosis and COVID-19 Lung lesions Revealed by High-Resolution Three-Dimensional Imaging

Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19 lungs, at near-microscopic levels ....

Kwazulu Natal , South Africa , Eastern Cape , South African , Adrie Steyn , Kapongo Lumamba , Joeln Glasgow , Kievershen Nargan , Alex Sigal , Threnesan Naidoo , Department Of Microbiology , University Of Kwazulu , Africa Health Research Institute , University Of Alabama At Birmingham , Gordon Wells ,