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Cancer Conundrum: Immune Checkpoint Inhibitor Use in Transplant Recipients

Randomized clinical trials of ICIs have traditionally excluded immunocompromised individuals, but emerging evidence suggests the drugs have the potential to treat advanced cancers in transplant recipients. Clinicians face a challenge in the use of immune checkpoint inhibitor therapy in organ transplant recipients because of their need for immunosuppression. ....

United States , New York , University Of Washington , Piyushk Agarwal , Kenard Jhaveri , Organ Procurement Transplantation Network , Bladder Cancer Program , Society Of Urologic Oncology , Drug Administration , University Of Chicago , Zucker School Of Medicine At Hofstra Northwell , Kidney International , Journal Of The National Comprehensive Cancer Network , International Journal Of Cancer , Urologic Oncology , Zucker School , National Comprehensive Cancer Network , International Journal , American Journal , Organ Procurement , Data Report ,