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Weird things shoplifters have stolen from Berkshire stores


SHOPLIFTERS of small and large items are always appearing in court charged with taking what isn’t theirs.
Here are some shoplifters from around Berkshire who have been in the dock for thieving over the past few weeks.
Laura Mason, stole meat worth £280 from a Co-op supermarket on two days back in June 2020.
Having previously pleaded guilty, the 42-year-old from Washington Drive in Slough changed her plea at Reading Magistrates Court earlier this month.
She was due to appear at Slough Magistrates Court again on Friday, April 16.
Leanne McDonald nicked perfume and other goods totalling more than £1,100 from Sainsbury’s in August of last year. ....

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PI3K/AKT/mTOR Inhibitors for Prostate Cancer – Finally Hints of a Breakthrough


PI3K/AKT/mTOR Inhibitors for Prostate Cancer – Finally Hints of a Breakthrough
Published 05 January 2021
Activation of the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway has been strongly linked with prostate cancer progression and metastatic potential.
1 Loss of the inhibitory phosphatase, PTEN, leading to hyperactivation of PI3K/AKT/mTOR oncogenic signaling, occurs in 40-50% of metastatic castration-resistant prostate cancer.
1,2 Not surprising is the fact that PTEN loss in patients with metastatic castration-resistant prostate cancer is associated with a worse prognosis and less benefit from androgen receptor (AR) blockade.
3 Likewise, PTEN loss and subsequent Akt activation confer radiation ....

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