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Chutes & Ladders—GlaxoSmithKline snags Pfizer vax leader Dormitzer

GlaxoSmithKline poached Pfizer's RNA and viral vaccines leader Phil Dormitzer, M.D., Ph.D., to shore up its vaccine business as it's lost many research staffers this past year. Parthenon Therapeutics snagged Johnson & Johnson's global head of cell therapy platform and discovery, Tamas Oravecz, Ph.D. And Rafael parted ways with five execs and reinstalled telecom tycoon Howard Jonas as CEO. ....

United States , Kristen Stewart , Padma Kodukula , Karl Hansen , Calithera Biosciences , Marco Marotta , Jullian Jones , Joseph Smith , Alex Van Belkum , Charmaine Lykins , Keith Orford , Lihua Yu , A Alpha Bio , Heather Getz , Carmel Lynch , Philippe Tinmouth , Jessie Richardson , Jeremy Meinen , Steven Petrou , Alyssa Wyant , Andreas Grauer , David Giarracco , Steven Chan , Juho Jalkanen , Johnson Janssen , Howard Jonas ,

Calithera Biosciences Inc (CALA) Q1 2021 Earnings Call Transcript


Operator
Good day, and thank you for standing by. Welcome to the Calithera Biosciences First Quarter 2021 Earnings Call. [Operator Instructions]
I would now like to hand the conference over to your first speaker today, Stephanie Wong. Please go ahead.
Stephanie Wong
Chief Financial Officer
Thanks, Jeff. Good afternoon, everyone. Welcome to our first quarter 2021 Conference Call. Joining me today are Susan Molineaux, Founder, President and CEO; and Keith Orford Chief, Medical Officer.
Earlier this afternoon, we issued a press release, which included an overview of our first quarter 2021 financial and operational results, which can be accessed through our website at calithera.com. Before we begin, I would like to remind you that today s discussion will include statements about our future expectations, plans and prospects that constitute forward-looking statements for purposes of the Safe Harbor provisions under the Private Securities Litigation Reform Act ....

Stephanie Wong , Susanm Molineaux , Susan Molineaux , Keith Orford , Calithera Biosciences Inc , Cystic Fibrosis Foundation , Calithera Biosciences First Quarter , Keith Orford Chief , Safe Harbor , Private Securities Litigation Reform Act , Risk Factors , Chief Executive , மாற்றாந்தாய் வோங் , கேய்ட் ஆர்ஃபர்ட் , சிஸ்டிக் ஃபைப்ரோஸிஸ் அடித்தளம் , பாதுகாப்பானது துறைமுகம் , ப்ரைவேட் பத்திரங்கள் வழக்கு சீர்திருத்தம் நாடகம் , ஆபத்து காரணிகள் , தலைமை நிர்வாகி ,

Giving Immunotherapy a Helping Hand


Giving Immunotherapy a Helping Hand
Source: Christoph Burgstedt/Science Photo Library/Getty Images
Giving Immunotherapy a Helping Hand
If adjusting one signal or hitting one target won’t force cancer to retreat, try adjusting multiple signals or deploying combination therapies
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Immunotherapy for cancer represents a promising alternative for many patients, but so far, it hasn’t delivered long-term benefits to a majority of patients as a standalone therapy. Fortunately, the immune system, with its complex webs of interacting networks and feedback pathways, offers myriad factors that drugs may target to summon tumor-killing resources.
Druggable factors in the tumor microenvironment are now being sought by many developers. When these factors are engaged by therapeutic molecules, it is possible to clear away immune suppressors, to boost the cytotoxicity of immune cells, or to weaken a tumor’s defenses. ....

John Lin , Calithera Biosciences , Dhan Chand , Cabozantinib Exelixis , Peter Lamb , Keith Orford , Tom Dubensky , Cancer Cell , ஜான் லின் , தன் மந்திரம் , பீட்டர் ஆட்டுக்குட்டி , கேய்ட் ஆர்ஃபர்ட் , புற்றுநோய் செல் ,