Live Breaking News & Updates on Keiko Iwaisako

Stay updated with breaking news from Keiko iwaisako. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Selective, toxin-bearing antibodies could help treat liver fibrosis


 E-Mail
IMAGE: Normal liver tissues (left) do not produce mesothelin, while liver tissue from patients with primary sclerosing cholangitis do (right, darker staining). Mesothelin is a marker of liver fibrosis, and the.
view more 
Credit: UC San Diego Health Sciences
Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.
So we thought.what if we take immunotoxins and try to get them to kill collagen-producing cells in the liver, said team lead Tatiana Kisseleva, MD, PhD, associate professor of surgery at UC San Diego School of Medicine. If these antibodies carrying toxic molecules can find and bind the cells, the cells will eat up the gift and die. ....

San Diego , United States , University Of California San Diego , Kojiro Taura , Takahiro Nishio , Jacopo Baglieri , Tapank Bera , Jamess Hagood , Yukinori Koyama , Tatiana Kisseleva , Keiko Iwaisako , Gen Yamamoto , Lauran Brenner , Ira Pastan , Davida Brenner , Nicholasf Larusso , Xiao Liu , Sarab Rosenthal , Doshisha University , National Cancer Institute , Shangai University Of Medicine , Kyoto University , National Institutes Of Health , Harvard Medical School , Proceedings Of The National Academy Sciences , University Of North Carolina At Chapel Hill ,