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Scientists at the Queen’s University of Belfast and the University of Birmingham have found a variety of cancers with mutations in the SF3B1 gene that forms part of the cellular splicing machinery respond to existing drugs that inhibit the enzyme poly ADP ribose polymerase (PARP). Currently PARP inhibitors used to treat cancers with mutations in the BRCA1 and BRCA2 genes. With PARP inhibitors already widely available, the study indicates it may be possible to treat patients with rare and difficult-to-treat cancers bearing mutations in SF3B1, using these repurposed drugs. ....
A DEFECTIVE gene normally found in blood cancers can be treated with existing drugs that will ultimately improve survival rates, Belfast scientists have discovered. ....
A defective gene, normally found in blood cancers, could be treated with drugs already available for cancers with similar gene defects, scientists at Queen’s University Belfast and the University of Birmingham have revealed. ....
Scientists at Queen’s University Belfast and the University of Birmingham have revealed that tumours normally found in blood cancers with mutations in the SF3B1 gene, are capable of responding to some existing PARP inhibitors, a type of drug used to treat cancers which carry similar mutations in the BRCA1 and BRCA2 genes. Click to read more. ....
Blood cancer case drop during pandemic 'a real concern' say Leukaemia & Lymphoma NI belfastlive.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from belfastlive.co.uk Daily Mail and Mail on Sunday newspapers.