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The Biorisk Management Casebook: Insights into Contemporary Practices

The Biorisk Management Casebook: Insights into Contemporary Practices
nti.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nti.org Daily Mail and Mail on Sunday newspapers.

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Pathogenic sensor's surprising capabilities revealed

Pathogenic sensor's surprising capabilities revealed
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Kyv Hoang , Jeffrey Tabor , Ken Groszman , Sky Hoang , Johns Gunn , John Gunn , Bretth Pogostin , Brett Pogostin , Kevinp Lorch , Kevin Lorch , Jeff Tabor , Jeffreyj Tabor , Maxwell Hunt Rice University Jeffrey Tabor Photo , Rice University Ph , Gustavo Raskosky Rice University , National Institutes Of Health , Massachusetts Institute Of Technology , Ohio State University , Stanford University School Of Medicine , National Science Foundation , Welch Foundation , Jeff Fitlow Rice University , Maxwell Hunt Rice University , Illustration Of Rice University , Rice University , Kathryn Brink ,

Engineered organism could diagnose Crohn's disease flareups

Rice University researchers have engineered a bacterium capable of diagnosing a human disease, a milestone in the field of synthetic biology. ....

United States , Rice University , Ian Cartwright , Sean Colgan , Jeffrey Tabor , Jeff Tabor , Rice Brown School Of Engineering , National Science Foundation , Natural Sciences , University Of Colorado Cu School Medicine , Jeff Tabor Rice University , Welch Foundation , Jeff Fitlow Rice University , Cu School Of Medicine , Proceedings Of The National Academy Sciences , University Of Colorado School Medicine , Baker Institute For Public , Rice University Systems , Department Of Medicine , Princeton Review , National Academy , Brown School , Kathryn Brink , Levine Kern Professor , Physical Biology , Colorado School ,

E. Coli Engineered to Diagnose Inflammatory Bowel Disease

E. Coli Engineered to Diagnose Inflammatory Bowel Disease
Source: boonchai wedmakawand/Getty Images
May 17, 2021
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Rice University researchers say they have engineered a bacterium with the necessary capabilities for diagnosing a human disease. The engineered strain of the gut bacteria
E. coli senses pH and glows when it encounters acidosis, an acidic condition that often occurs during flareups of inflammatory bowel diseases like colitis, ileitis, and Crohn’s disease, according to the scientists.
Researchers at the University of Colorado (CU) School of Medicine used the Rice-created organism in a mouse model of Crohn’s disease to show acidosis activates a signature set of genes. The corresponding genetic signature in humans has previously been observed during active inflammation in Crohn’s disease patients. The study (“Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphor ....

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