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Researchers Uncover Potential Causes of Chronic Allergy Inflammation

Researchers Uncover Potential Causes of Chronic Allergy Inflammation
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United States , Maria Gutierrez Arcelus , Erinm Taylor , Joshuaa Boyce , Caitlinm Burk , Alanna Mcgill , Bristol Myers Squibb , Garrett Dunlap , Kathleenm Buchheit , Tanyam Laidlaw , Deepaka Rao , Reganw Bergmark , Raghup Kataru , Babakj Mehrara , Rachel Roditi , Estella Lee , Shailesh Agarwal , Patrick Brennan , Jessicar Allegretti , Danielf Dwyer , Sanofi Aventis Regeneron , Alicez Maxfield , Sarah Djeddi , Tessa Ryan , Xiaojiong Jia , Radomir Kratchmarov ,

Dupilumab improves outcomes in aspirin-exacerbated respiratory disease

By inhibiting IL-4R alpha in aspirin-exacerbated respiratory disease, dupilumab improved respiratory symptoms and smell among other positive outcomes, according to a study published in The Journal of Allergy and Clinical Immunology. These therapeutic effects likely are due to decreased IL-4R alpha signaling on respiratory tissue granulocytes, epithelial cells and B cells, Kathleen M. Buchheit, ....

Kathleenm Buchheit , Regeneron Sanofi , University Of Pennsylvania Smell Identification Test , Harvard Medical School , Immunology Clinics , Pennsylvania Smell Identification Test , Asthma Control Questionnaire ,