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Patterns in Resistance to CAR-T Therapy in Patients With Acute Lymphoblastic Leukemia

Researchers identified gene regulation patterns that may help predict response to CAR-T therapy in patients with acute lymphoblastic leukemia. ....

United States , United Kingdom , Javed Khan , Katherinee Masih , National Cancer Institute In Bethesda , University Of Cambridge , National Cancer Institute , Seattle Children ,

Biomarker Predicts Nonresponse to CAR T in Pediatric ALL

Alternative strategies could be offered to children and young adults with advanced acute lymphoblastic leukemia (ALL) identified as being unlikely to respond to the expensive therapy. ....

United States , United Kingdom , New Jersey , Javed Khan , Maria Lopez , Katherinee Masih , Jefferson Health New Jersey , National Cancer Institute , Sidney Kimmel Cancer Center , Genetics Branch , Cancer Research , American Association For Cancer Research , Baldrick Foundation , Seattle Children Research Institute , Cambridge Scholars Program , American Association , Annual Meeting , Ana Maria Lopez , Washington Township , Seattle Children , Transposase Accessible Chromatin , Research Institute , Strong Against Cancer , Lemonade Stand , Cambridge Scholars , Acute Leukemia ,