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Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer-;but not every mutation in the gene is harmful.

United statesJason gertzDavid goldgarKatherine varleyKenneth boucherSean tavtigianAlun thomasEmily hendersonLady davis institute for medical researchIu school of medicineHuntsman cancer instituteNational institutes of healthUniversity of utahCanadian institutes of health researchMcgill universityAmerican college of medical genetics