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COVID-19 Antibody Treatment Approved for Unvaccinated Family Members With Weak Immunities


Monoclonal Antibody Treatments Defined
The new treatment was initially allowed for limited use and administered as an IV infusion cocktail, alongside medications like casirivimab and imdevimab, within ten days of the patient s symptoms manifestation. However, with the FDA s newest approval, the treatment may now be administered within 96 hours after the exposure.
To gain clearance from the FDA, the pharmaceutical company had a clinical trial among a larger group composed of families exposed to contacts with COVID-19 in the U.S. Moldova and Romania. Of the 1,505 participants, 81 percent who took the cocktail had reduced risks of hospitalization and severe symptoms from the virus. The affected patients also had shorter symptoms of the virus clearing faster than if they did not get the IV infusion. ....

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Regeneron's antibody drug can help prevent covid-19 from spreading among household members


The Philadelphia Inquirer
Star Tribune
Vials are inspected at Regeneron Pharmaceutical’s facilities in New York state, for efforts on an experimental coronavirus antibody drug.
 
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PHILADELPHIA Drugs that can keep high-risk covid-19 patients out of the hospital are going begging because the supposed breakthrough treatments require an hour-long intravenous infusion and offer a rather small chance of benefit.
On Monday, Regeneron announced results that may help make its monoclonal antibody combination, now branded REGEN-COV, more useful. The drug combo was given in a single shot and dramatically reduced the chance of infection in unvaccinated individuals living with someone newly diagnosed with covid-19. ....

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Regeneron COVID-19 antibody cocktail helps prevent symptomatic disease in study


Infectious disease doctor Dr. Amesh Adalja on several states see spike in coronavirus cases.
A monoclonal antibody cocktail developed by Regeneron and Roche dropped the risk of symptomatic COVID-19 by up to 76% after three days for recently infected individuals not yet experiencing symptoms, according to a press release posted Monday. The drug, REGEN-COV, also significantly reduced duration of symptoms and lowered viral levels, Regeneron said.
REGEN-COV, comprised of casirivimab with imdevimab, has already received emergency use authorization from the FDA in the U.S. Under the current EUA, the combo therapy is approved to treat non-hospitalized adults and adolescents with mild to moderate symptoms of COVID-19 and who are at high risk for developing severe symptoms or the need for hospitalization. ....

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