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Same difference: Two halves of the hippocampus have different gene activity


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IMAGE: Marked differences in gene activity were identified in the anterior portion of the hippocampus, which points downward toward the face, and the posterior, which points upward toward the back of.
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Credit: Melissa Logies
DALLAS - May 28, 2021 - A study of gene activity in the brain s hippocampus, led by UT Southwestern researchers, has identified marked differences between the region s anterior and posterior portions. The findings, published today in
Neuron, could shed light on a variety of brain disorders that involve the hippocampus and may eventually help lead to new, targeted treatments.
These new data reveal molecular-level differences that allow us to view the anterior and posterior hippocampus in a whole new way, says study leader Genevieve Konopka, Ph.D., associate professor of neuroscience at UTSW. ....

United States , University Of Texas , Karthigayini Sivaprakasam , Genevieve Konopka , Connor Douglas , Peter Odonnell Jr , Fatma Ayhan , Ashwinikumar Kulkarni , Jon Heighten Scholar In Autism Research , National Center , National Institutes Of Health , Chan Zuckerberg Initiative , Translational Sciences , Brain Institute , Jamess Mcdonnell Foundation , Silicon Valley Community Foundation , Century Science Initiative In Understanding Human Cognition , Chilton Foundation , Jon Heighten Scholar , Autism Research , Petero Donnell , Stefano Berto , National Institutes , Advancing Translational Sciences , Translational Medicine , Odonnell Foundation ,