Live Breaking News & Updates on Kanzawa Medical Research

Credit: Khalid Shah lab, Brigham and Women s Hospital
Approximately 15-to-30 percent of patients with metastatic breast cancer have brain metastasis (BM), with basal-like breast cancer (BLBC) metastasizing to the brain most frequently. The prognosis for BLBC-BM patients is poor, as the blood-brain barrier prevents most therapeutics from reaching the brain. Testing candidate therapies in clinical trials is also challenging because animal models that mimic BM are limited. In a new study, researchers from Brigham and Women s Hospital and collaborators engineered a bimodal tumor-suppressing and killing molecule that can be delivered to the brain by stem cells. They tested the therapy in three new mouse models of BLBC-BM that imitate human cancers and found that it successfully prolonged the lifespan of the mice. Findings are published in ....

Khalid Shah , Kanzawa Medical Research Foundation , Research Fellowships , Drug Administration , Brigham Department Of Neurosurgery , Uehara Memorial Foundation , Stem Cell Therapeutics , Overseas Research Fellowships , Kanzawa Medical Research , Medicine Health , Breast Cancer , காலிட் ஷா , ஆராய்ச்சி கூட்டுறவு , ப்ரிகாம் துறை ஆஃப் நரம்பியல் அறுவை சிகிச்சை , ஊஎர நினைவகம் அடித்தளம் , தண்டு செல் சிகிச்சை , ஓவர்‌ஸீஸ் ஆராய்ச்சி கூட்டுறவு , மருந்து ஆரோக்கியம் , மார்பக புற்றுநோய் ,