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Date Time Methadone research could help babies exposed to opioids in utero A study by researchers from the Indiana University School of Medicine in Indianapolis and the Gill Center for Biomolecular Science at IU Bloomington found that in-utero exposure to methadone in mice could negatively affect developmental milestones related to proper functioning of the brain’s sensory and motor systems. The findings could one day lead to new treatment options that reduce long-term damage to human babies from in-utero opioid exposure. “The opioid epidemic has led to a growing number of babies being born to mothers who used opioids throughout pregnancy, but little is known of the biological mechanisms that underlie prenatal, opioid-exposure-induced, long-term negative consequences,” said study lead Brady Atwood, assistant professor of pharmacology and toxicology at the IU School of Medicine. “Our findings revealed a disruption in physical, behavioral and neuronal development ....