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Spike protein-human cell binding mechanism holds clue to Covid drugs, IIT Madras study claims


Spike protein-human cell binding mechanism holds clue to Covid drugs, IIT Madras study claims
According to the study, understanding spike protein interactions at ACE2 receptor site in humans will help find ways to reduce severity of coronaviruses and treatment options.
Soniya Agrawal 27 April, 2021 8:17 am IST
A+
New Delhi: The reason for the devastating transmission and infection of Covid-19, as compared to common-cold causing coronaviruses, is due to the high interaction energy and area between the spike protein of the SARS-CoV-2 virus and the human ACE2 receptor protein, seen as the entry point for the coronavirus to hook onto and infect a wide range of human cells, a study by IIT Madras has found. ....

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IIT Madras Studying Coronavirus Spike Protein For Permanent Covid-19 Treatment


IIT Madras Studying Coronavirus Spike Protein For Permanent Covid-19 Treatment
Indiatimes
3 hours ago
© Provided by Indiatimes
Why does the novel coronavirus have a ridiculously high transmission rate and mortality as compared to the common-cold causing coronaviruses, such as the HCoV-NL63, which was first identified in late 2004 in a seven-month-old child with bronchiolitis in the Netherlands?
The mildness and severity of disease caused by these viruses depends on the interaction energy and the interaction area between spike protein of the coronavirus and ACE2 receptors of human cells, the researchers at the Indian Institute of Technology (IIT) Madras said in a new study. ....

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