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IIT Madras Researchers study the high transmission potential of Coronavirus


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Chennai: Indian Institute of Technology Madras researchers are studying the high transmission rate and mortality of SARS-CoV-2, the scientific name for the coronavirus that causes COVID-19. Using computational tools, the team studied its two close variants – SARS-CoV and NL63.
The team set out to understand how the spike proteins (which enables the coronavirus to penetrate human cells and cause COVID-19) of these different virus strains are interacting with the ACE2 receptors of human cells and how this interaction is affecting their transmission potential and severity of the disease
‘SARS-CoV’ can be considered a ‘sibling’ of the subfamily beta coronavirus ‘SARS-CoV-2.’ The ‘NL63’ belongs to sub-family alpha coronavirus can be considered as a ‘cousin’ of SARS-CoV-2. SARS-CoV is more severe than SARS-CoV-2 whereas NL63 shows milder symptoms than SARS-CoV and SARS-CoV-2. ....

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