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Olaparib With/Without Cediranib Does Not Improve OS Vs Chemo in Recurrent Platinum-Sensitive Ovarian Cancer

The use of olaparib as a monotherapy or in combination with cediranib did not provide a statistically significance overall survival benefit compared with standard-of-care platinum-based chemotherapy in patients with recurrent, platinum-sensitive ovarian cancer. ....

United States , Dana Farber Cancer Institute , Joycef Liu , Harvard Medical School , Clinical Research Program , Division Of Gynecologic Oncology , Clinical Research , Gynecologic Oncology , Harvard Medical , Ovarian Cancer , Rg Gy004 Trial ,

Personal Organoids May Personalize Cancer Treatment

Personal Organoids May Personalize Cancer Treatment
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Ursulaa Matulonis , Anthony Letai , Yelena Ivanova , Michaeld Genovese , Joycef Liu , Miracles Foundation , Breast Cancer Research Fund , Michael Stansky Fund , Pan Mass Challenge Team Dedicated To , Genovese Fund , Dana Farber Cancer Institute , Belfer Family Foundation , Poster Session , Farber Cancer Institute , Mass Challenge Team Dedicated , Low Grade Serous Ovarian , Ovarian Cancer , Michael Stansky , Belfer Family ,

Adavosertib Appears Active but Toxic in Advanced Uterine Cancer

Adavosertib is active but not well tolerated in patients with recurrent or persistent uterine serous carcinoma, a phase 2 study suggests. ....

Dana Farber Cancer Institute , United States , Bristol Myers Squibb , Joycef Liu , Genentech Roche , Acetylon Pharmacuetical , Clovis Oncology , Arch Oncology , Boston Biomedical , Cytomx Therapeutics , Impact Therapeutics , Surface Oncology , Vegeo Therapeutics ,

Adavosertib Appears Active but Toxic in Advanced Uterine Cancer

Adavosertib is active but not well tolerated in patients with recurrent or persistent uterine serous carcinoma, a phase 2 study suggests. ....

United States , Dana Farber Cancer Institute , Joycef Liu ,

Tolerability Hinders Adavosertib Activity in Recurrent or Persistent Uterine Serous Carcinoma

Treatment with the oral, small-molecule Wee1 kinase inhibitor adavosertib was clinically active but not well tolerated in patients with recurrent or persistent uterine serous carcinoma who previously received platinum-based chemotherapy. ....

United States , Dana Farber Cancer Institute , Bristol Myers Squibb , Joycef Liu , Genentech Roche , Acetylon Pharmaceuticals , Gynecologic Oncology Annual Meeting , Gynecologic Oncology , Clovis Oncology , Arch Oncology , Boston Biomedical , Cytomx Therapeutics , Impact Therapeutics , Surface Oncology , Vigeo Therapeutics , Sgo Annual Meeting , Ingle Arm Phase 2b Adagio Trial , 2023 Society Of Gynecologic Oncology Annual Meeting On Womens Cancer ,