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Deep learning tool identifies mosaic mutations that cause disease

Genetic mutations cause hundreds of unsolved and untreatable disorders. Among them, DNA mutations in a small percentage of cells, called mosaic mutations, are extremely difficult to detect because they exist in a tiny percentage of the cells. ....

San Diego , United States , University Of California San Diego , Martinw Breuss , Jonathanl Sebat , Reneed George , Ludmilb Alexandrov , Chen Li , Joseph Gleeson , Xin Xu , Yuhe Cheng , Taejeong Bae , Aimee Molineuxjan , Danny Antaki , Jiawei Shen , Alexei Abyzov , Changuk Chung , Yifan Wang , Xiaoxu Yang , Rady Children Institute For Genomic Medicine , Uc San Diego School Of Medicine , Nature Biotechnology , California San Diego School , Rady Children , Genomic Medicine , Image Credit ,

New Computer Program 'Learns' to Identify Mosaic Mutations That Cause Disease

New Computer Program 'Learns' to Identify Mosaic Mutations That Cause Disease
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Chen Li , San Diego , United States , University Of California San Diego , Martinw Breuss , Jonathanl Sebat , Liping Wei , Reneed George , Ludmilb Alexandrov , Joseph Gleeson , Xin Xu , Yuhe Cheng , Taejeong Bae , Danny Antaki , Jiawei Shen , Alexei Abyzov , Changuk Chung , Yifan Wang , Xiaoxu Yang , San Diego Supercomputer Center , Uc San Diego Institute Of Genomic Medicine , Rady Children Institute For Genomic Medicine , National Institutes Of Health , Brain Somatic Mosaicism Network , Uc San Diego School Of Medicine , Nature Biotechnology ,

New Computer Program 'Learns' to Identify Mosaic Mutations That Cause Disease

New Computer Program 'Learns' to Identify Mosaic Mutations That Cause Disease
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Chen Li , San Diego , United States , University Of California San Diego , Martinw Breuss , Jonathanl Sebat , Liping Wei , Reneed George , Ludmilb Alexandrov , Joseph Gleeson , Xin Xu , Yuhe Cheng , Taejeong Bae , Danny Antaki , Jiawei Shen , Alexei Abyzov , Changuk Chung , Yifan Wang , Xiaoxu Yang , San Diego Supercomputer Center , Uc San Diego Institute Of Genomic Medicine , Rady Children Institute For Genomic Medicine , National Institutes Of Health , Brain Somatic Mosaicism Network , Uc San Diego School Of Medicine , Nature Biotechnology ,