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Impressive Results With Lenvatinib in Challenging Tumors


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The multitargeted tyrosine kinase inhibitor (TKI) lenvatinib induced a strong tumor response in patients with previously treated advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs), according to results from a phase II trial in Europe.
In this multicenter, open-label study involving 111 patients, treatment with lenvatinib (Lenvima) led to an overall response rate (ORR) of 29.9%, with a particularly high ORR 44.2% in patients with pancreatic NETs, reported Jaume Capdevila, MD, PhD, of Vall Hebron University Hospital in Barcelona, and colleagues
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This study provides novel evidence for the efficacy of lenvatinib in patients with disease progression following treatment with other targeted agents, suggesting the potential value in the treatment of advanced GEP-NETs, they wrote in the ....

Israel General , United States , Comunidad Autonoma De Cataluna , Jonathan Strosberg , Jaume Capdevila , Mike Bassett , Vall Hebron University Hospital , Moffitt Cancer Center , இஸ்ரேல் ஜநரல் , ஒன்றுபட்டது மாநிலங்களில் , காமுனிடட தன்னாட்சி டி கடலுள் , ஜொஊமே சாப்டேவில , மைக் பாசெட் , மாஃபிட் புற்றுநோய் மையம் ,