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Fresh Air Extends Lifespan of Drug-Producing Cells

Fresh Air Extends Lifespan of Drug-Producing Cells
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Tzahi Cohen Karni , Omid Veiseh , Abhijith Surendran , Minkyu Lee , Jonathan Rivnay , Rice University , Northwestern Mccormick School Of Engineering , Carnegie Mellon University , Nature Communications , Defense Advanced Research Projects Agency , Northwestern University Led , Mccormick School , Normalizing Timing , Rhythms Across Internal Networks , Circadian Clocks ,

Rice Biotech Unveils Rechargeable Oxygenator for Cell Therapies

Rice Biotech Unveils Rechargeable Oxygenator for Cell Therapies
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Tzahi Cohen Karni , Omid Veiseh , Abhijith Surendran , Minkyu Lee , Carnegie Mellon University , Nature Communications , Northwestern University Jonathan Rivnay , Rice University , Defense Advanced Research Projects Agency , Biotech Launch Pad , Rice Biotech Launch Pad , Northwestern University , Jonathan Rivnay , Rice Biotech Launch ,

A breath of fresh air keeps drug-producing ce

<p>Researchers have developed a novel device that produces oxygen inside of a &quot;living pharmacy&quot; implant in order to keep cells alive inside the self-contained device. The device produses oxygen through a&nbsp;smart, energy-efficient version of water splitting.&nbsp;In new experiments, the novel device&nbsp;kept cells (70-80%) alive for close to a month in low oxygen conditions in vitro, or weeks in vivo. Without ecO<sub>2</sub>, only about 20% of cells were alive after 10 days, but the researchers hypothesize that the cells would lose their ability to secrete drugs long before that. Cell-based therapies show promise for drug delivery, replacing damaged tissues, harnessing the body&rsquo;s own healing mechanisms and more.&nbsp;The longer cells can stay alive and healthy, the longer they can autonomously produce therapeutics for the body.</p>
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Minkyu Lee , Omid Veiseh , Tzahi Cohen Karni , Abhijith Surendran , Jonathan Rivnay , Rice University , Research Projects Agency , Method Of Research , Carnegie Mellon University , Nature Communications , Mccormick School Of Engineering , Northwestern University Led , Advanced Research Projects Agency , Cormick School , Normalizing Timing , Rhythms Across Internal Networks , Circadian Clocks ,

$45 million granted to NU cancer therapy device project

The Advanced Research Projects Agency for Health awarded researchers at Northwestern and seven other institutions a $45 million grant to continue developing a small, implantable device that could detect and treat cancer, NU announced Tuesday. The multi-institutional effort is funded by the agency, which aims to fast-track novel cancer technologies. The Biden-Harris administration recently pledged. ....

Jonathan Rivnay , Research Projects Agency For Health , Advanced Research Projects Agency , Cancer Moonshot ,