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Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution. They analyzed the genomes of more than 2,800 individuals who lived in Europe over the past ten millennia. They were able to date the increase in frequency of most of the mutations that are advantageous in defending against pathogens to after the Bronze Age, 4,500 years ago. ....

France General , New York , United States , Rockefeller University , Anne Puel , Laurent Abel , Lluis Quintana Murci , Darawan Rinchai , Institut Pasteur , Anna Lena Neehus , Gaspard Kerner , Etienne Patin , Shen Ying Zhang , Nacim Kerrouche , Jonathan Bohlen , Quentin Philippot , Jean Laurent Casanova , Health Unit Universit , France Foundation , Rockefeller University United States , French Foundation For Medical Research , Department Of Pediatrics , Laboratory Of Human Genetics Infectious Diseases , University Paris Cit , Howard Hughes Medical Institute , Paris Cit ,