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Scientists uncover new molecular drivers of Alzheimer's

According to the US Centers for Disease Control and Prevention, at least 5.8 million Americans are currently living with Alzheimer s disease, which is the most common form of dementia. There is no cure for Alzheimer s, in part because scientists do not yet have a full understanding of what causes the disease. But a new study from Scripps Research is shedding light on the molecular drivers that could contribute to Alzheimer s progression. ....

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Super-Enhancer Accelerates Pancreatic Tumor Growth

Super-Enhancer Accelerates Pancreatic Tumor Growth
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San Diego , United States , United Kingdom , Salk Institute , New South Wales , Jonas Salk , Morganl Truitt , Nicolem Sodir , Andrewm Lowy , Ronald Evans , Ching Luo , Rutht Yu , David Propper , Jolenek Diedrich , Edgar Esparza , Erkut Borazanci , Tania Campos , Ruben Munoz , Briana Yee , Christopher Liddle , Janc Lumibao , Annetter Atkins , Haiyong Han , Gabriela Estepa , Katherinel Rothamel , Zhang Cheng ,

"Super-enhancer" super-charges pancreatic tum

Salk scientists identified new set of molecules that drive the growth of human pancreatic cancer cell lines, explaining how genetic mutations can activate genetic "super-enhancers" that promote out-of-control pancreatic cancer growth. They show the efficacy of an experimental drug that targets a super-enhancer related protein, demonstrating the promise of therapeutics that block the effects of super-enhancers. ....

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