Alzheimer's disease (AD) is linked to harmful protein accumulations in the brain, primarily β-amyloid (Aβ) aggregates known as plaques, which are central to the disease's pathology. Entresto (sacubitril/valsartan) is a combined neprilysin inhibitor and angiotensin receptor blocker, approved for the
Study results suggest a gap between guideline-recommended medical therapy and prescription of drugs to frail patients with heart failure with reduced ejection fraction.
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