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A New Way to Make Chemicals Not Found in Nature

Adapted from a UC Berkeley news release. Synthetic biologists have successfully engineered microbes to make chemicals cheaply and more sustainably. However, researchers have been limited by the fact that microbes can only make molecules using chemical reactions seen in nature. A collaboration between scientists at Berkeley Lab and UC Berkeley has engineered the microbe E. coli to produce a molecule that, until now, could only be synthesized in a laboratory. To achieve this outcome, the researchers integrated a specific type of modified enzyme into E. coli, along with a pathway to produce a precursor molecule. This was then converted into ....

United States , Brandon Bloomer , Aindrila Mukhopadhyay , Jing Huang , Johnf Hartwig , Douglass Clark , Brandonj Bloomer , Jayd Keasling , Chemical Sciences Division Zhennan Liu , Bioenergy Institute , Bioenergy Research Center , Berkeley Lab , Us Department Of Energy , Bioproducts Division , Biosciences Area , Joint Bioenergy Institute , Chemical Sciences Division , Zhennan Liu ,