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J&J, Novavax Vaccines Offer Strong Protection Against Covid-19


Feb 2, 2021
Reduced efficacy seen in South African strain
Johnson & Johnson’s single-shot Covid-19 vaccine candidate was shown to be very effective overall, but significantly less effective against the highly contagious South African B.1.351 variant of the disease predicted by many to become the dominant form of SARS-CoV-2 infection in the United States by mid-spring.
Data from the ENSEMBLE trial, released Friday morning, showed the vaccine to have a 72% overall efficacy in U.S., with a 66% overall effectiveness for preventing moderate-to-severe disease 28 days after vaccination.
Trial data from South Africa, where the B.1.351 variant was the predominant strain at the time of the study, showed the single-shot J&J-Janssen Pharmaceuticals vaccine to be 57% effective. ....

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Johnson & Johnson one-dose COVID-19 shot offers strong protection, fuels concern about variants- Technology News, Firstpost


Johnson & Johnson one-dose COVID-19 shot offers strong protection, fuels concern about variants
A single-dose vaccine is a big advantage when most countries are struggling to get shots in arms more quickly.
Feb 01, 2021 14:57:16 IST
Johnson & Johnson, the only major drugmaker developing a single-dose vaccine for COVID, announced Friday that its shot provided strong protection against COVID-19, potentially offering another powerful tool in a desperate race against a worldwide rise in virus mutations. But the results came with a significant cautionary note: The vaccine’s efficacy rate dropped from 72% in the United States to 57% in South Africa, where a highly contagious variant is driving most cases. ....

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Johnson & Johnson one-dose COVID-19 shot offers strong protection, fuels concern about variants


Johnson & Johnson one-dose COVID-19 shot offers strong protection, fuels concern about variants
A single-dose vaccine is a big advantage when most countries are struggling to get shots in arms more quickly.
A participant in a Johnson & Johnson vaccine trial at the Desmond Tutu HIV Foundation Youth Center near Cape Town, South Africa, Dec. 5, 2020. Johnson & Johnson s vaccine’s efficacy rate dropped from 72 percent in the United States to 57 percent in South Africa, where a highly contagious variant is driving most cases. [Carl Zimmer, Noah Weiland, Sharon LaFraniere/Joao Silva] © 2020 The New York Times
Johnson & Johnson, the only major drugmaker developing a single-dose vaccine for COVID, announced Friday that its shot provided strong protection against COVID-19 ....

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