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Research could open the door to next-generation of cancer drugs that work better


Research could open the door to next-generation of cancer drugs that work better
Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new University of Colorado Boulder research.
The paper, published February 2 in the journal
Nature Communications, sheds new light on how they do work and could open the door to new next-generation medications that work better, the authors said.
Despite the success of these drugs which sell in the billions of dollars per year and treat many thousands of patients, there are many unknowns about their potency and efficacy that if better understood could lead to improvements. Our paper provides a fuller picture. ....

United States , Genevieve Roberts , Johannes Rudolph , Karolin Luger , Emily Henderson , Nature Communications , University Of Colorado Boulder , Department Of Biochemistry , Colorado Boulder , Senior Author , Breast Cancer , Dna Damage , ஒன்றுபட்டது மாநிலங்களில் , ஜெநிவீவ் ராபர்ட்ஸ் , ஜோஹன்னஸ் ருடால்ப் , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் கொலராடோ கற்பாறை , துறை ஆஃப் உயிர் வேதியியல் , கொலராடோ கற்பாறை , மூத்தவர் நூலாசிரியர் , மார்பக புற்றுநோய் , உயிர் வேதியியல் , டீயெநே சேதம் ,

Popular breast cancer drugs don't work the way we thought they did


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Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new University of Colorado Boulder research.
The paper, published February 2 in the journal
Nature Communications, sheds new light on how they do work and could open the door to new next-generation medications that work better, the authors said.
Despite the success of these drugs which sell in the billions of dollars per year and treat many thousands of patients, there are many unknowns about their potency and efficacy that if better understood could lead to improvements, said senior author Karolin Luger, a professor in the Department of Biochemistry. Our paper provides a fuller picture. ....

United States , Genevieve Roberts , Johannes Rudolph , Karolin Luger , Nature Communications , University Of Colorado Boulder , Department Of Biochemistry , Colorado Boulder , ஒன்றுபட்டது மாநிலங்களில் , ஜெநிவீவ் ராபர்ட்ஸ் , ஜோஹன்னஸ் ருடால்ப் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் கொலராடோ கற்பாறை , துறை ஆஃப் உயிர் வேதியியல் , கொலராடோ கற்பாறை ,