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Follow RT on A Spanish study has suggested that administering a second dose of Pfizer to those who received AstraZeneca as their first dose is safe. It saw antibodies increase seven-fold compared to those who were given no second jab at all. The CombivacS study, which enrolled 676 participants who had already received a first dose of AstraZeneca and gave them a second dose of Pfizer, has produced positive preliminary results. Of the total cohort, 450 people were given Pfizer as their second dose, and the remaining 226 have not received any second dose and are being observed as the control group. Published on Tuesday, the study, launched by the Carlos III Health Institute, reported that the combination was both safe and effective. Jesus Antonio Frias, coordinator of the ISCIII Clinical Research Network, said, ....
May 19, 2021 A vial of AstraZeneca coronavirus vaccine is seen at a vaccination centre. Reuters MADRID - A Spanish study on mixing Covid-19 vaccines has found that giving a dose of Pfizer s drug to people who already received a first shot of AstraZeneca vaccine is highly safe and effective, preliminary results showed on Tuesday (May 18). The Combivacs study, run by Spain s state-backed Carlos III Health Institute, found the presence of IgG antibodies in the bloodstream was between 30 and 40 times higher in people who got the follow-up Pfizer shot than in a control group who received only one AstraZeneca dose. Meanwhile, the presence of neutralising antibodies rose sevenfold after a Pfizer dose, significantly more than the doubling effect observed after a second AstraZeneca shot. ....
Spanish study finds AstraZeneca vaccine followed by Pfizer dose is safe and effective Published May 19, 2021 7:46am Needles and a vial of AstraZeneca s vaccine against COVID-19 are pictured during a pilot test which aims to apply 20,000 vaccines per day in coming months, at Fira de Montjuic in Barcelona, Spain, April 26, 2021. A Spanish study found that giving a dose of Pfizer s vaccine as a follow-up to an AstraZeneca jab is safe and effective. REUTERS/Nacho Doce MADRID - A Spanish study on mixing COVID-19 vaccines has found that giving a dose of Pfizer s drug to people who already received a first shot of AstraZeneca vaccine is highly safe and effective, preliminary results showed on Tuesday. ....
The mix-match study, called CombiVacS, is the first in the world to provide data on the immune response when the vaccine from Pfizer and BioNTech is given after a dose of AstraZeneca s vaccine. Antibody levels were about 40 times higher for those who got Pfizer s vaccine two weeks after AstraZeneca s, compared with participants who got a single AstraZeneca dose, the researchers from Carlos III Health Institute said in a presentation of preliminary results. The group found that neutralizing antibodies that fight off the virus were boosted more than seven times higher after the dose of Pfizer s shot. This is higher than described elsewhere with two doses of the same vaccine, they said. ....
Spanish study finds mixing Pfizer, AstraZeneca jabs effective 19 May 2021 10:52 Share in: OVIEDO. KAZINFORM Vaccinating coronavirus patients who have received the AstraZeneca jab with the Pfizer vaccine is safe and effective, according to preliminary results from a Spanish study published Tuesday. Related news The small clinical trial led by Spain’s Carlos III Health Institute found that mixing the vaccines could provide greater protection against the virus, Anadolu Agency reports. The neutralizing antibodies in the people who received a second dose of the Pfizer vaccine increased sevenfold compared to those who received just one AstraZeneca dose. It is a higher increase than previous studies found when two doses of AstraZeneca were given, according to the public health institute. ....