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Cell Fate: Another Hurdle for Evolution

When a stem cell divides, one daughter cell must maintain its stemness while the other specializes. Therein lies another truckload of requirements. ....

United States , Iqbal Pittawala , Sihem Cheloufi , Jernej Murn , Neil Thomas , Nature Communications , Researchers At University Of California Riverside , Control Terms ,

How genome organization influences cell fate

How genome organization influences cell fate
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Palm Desert , United States , Coachella Valley , David Sykes , Yiming Guo , Carmen Chiem , Reuben Franklin , Jernej Murn , Russell Rockne , Meijuan Chen , Ruslan Sadreyev , Sihem Cheloufi , Maria Ninova , Andrew Volk , University Of California , Nature Communications , Palm Desert Center , Department Of Defense , National Institutes Of Health , Department Of Biochemistry , Cincinnati Children Hospital Medical Center , Cincinnati Children , Hospital Medical Center , Massachusetts General , National Institutes , Chromatin Accessibility ,

Study illustrates how a protein complex controls genome organization to maintain lineage fidelity

Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in molecular and cellular biology, with critical implications for the treatment of human diseases. Central to the cell fate decision process are stem cells residing within each tissue of the body. ....

United States , Sihem Cheloufi , Jernej Murn , Andrew Volk , Emily Henderson , University Of California , Nature Communications , Cincinnati Children Hospital Medical Center , Department Of Biochemistry , Assistant Professor , Cincinnati Children , Hospital Medical Center , Bone Marrow , Cell Division , Cellular Biology , Progenitor Cells , Stem Cells , Transcription Factors ,

UC grapples with allegations of funding inequities, racism

UC grapples with allegations of funding inequities, racism
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United States , San Diego , San Bernardino Valley College , Deidre Reyes , Michaelv Drake , Kiki Chavez , Jennifer Brown , Nathan Brostrom , Jennifer Le , Santa Barbara , Irfan Khan Los Angeles , Yvonne Marquez , Casaundra Caruso , Gilbert Marquez , Kim Wilcox , Janet Napolitano , Melissam Wilcox , Gina Ferazzi Los Angeles , Jernej Murn , Robert Jinkerson , Helen Regan , Yvonne Marqu , Carol Christ , George Blumenthal , University Of California , College Of Humanities ,