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New drug candidates targeting blood clots developed through computer-aided drug design

A team of Vanderbilt researchers has created a new series of drug candidates against a hard-to-target receptor involved in the formation of blood clots. The research, spearheaded by the labs of Jens Meiler, research professor of chemistry, Craig Lindsley, Executive Director of Warren Center for Neuroscience Drug Discovery and professor of pharmacology, and Heidi Hamm, the Aileen M. Lange and Annie Mary Lyle Professor of Cardiovascular Research and professor of pharmacology, was published in ACS Pharmacology and Translational Science in March 2024. ....

Craig Lindsley , Jens Meiler , Shannont Smith , Aileenm Lange , Shannon Smith , Heidi Hamm , Annie Mary Lyle Professor Of Cardiovascular Research , Warren Center , Translational Science , Executive Director , Neuroscience Drug Discovery , Annie Mary Lyle Professor , Cardiovascular Research , Protease Activated Receptor ,

Mystery of Tumor Receptor Behavior Solved by Case Western, MetroHealth

Mystery of Tumor Receptor Behavior Solved by Case Western, MetroHealth
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United States , Josephineb Wootton , Ben Brown , Jens Meiler , Dolores Hambardzumyan , Adamw Smith , John Chae , Dimitarb Nikolov , Xiaojun Roger Shi , Khalid Sossey Alaoui , Bingcheng Wang , Memorial Sloan Kettering Cancer Center , Case Comprehensive Cancer Center , Metrohealth Research Institute , Vanderbilt University , School Of Medicine , Icahn School Of Medicine At Mount Sinai , Texas Tech University , Metrohealth Division Of Cancer Biology , Case Western Reserve School Of Medicine , Case Western Reserve University , Endowed Chair , Case Western Reserve School , Case Comprehensive Cancer , Metrohealth Division , Cancer Biology ,

Machine versus virus: Deploying artificial intelligence against future pandemics

AI is being used to design vaccines for viruses we don’t even know about yet. ....

Clara Schoeder , Jens Meiler , Coalition For Epidemic Preparedness Innovations , Vanderbilt University In Nashville , University Of Leipzig , Institute Of Drug Discovery , Vanderbilt University , Prof Jens Meiler , Drug Discovery , Epidemic Preparedness Innovations ,

Scientists set AI to work on finding vaccines to combat the next Disease X

Artificial intelligence will help build a ‘vaccine library’ for future scientists faced with the ‘inevitable’ outbreak of a novel pathogen ....

Jens Meiler , Richard Hatchett , Coalition For Epidemic Preparedness Innovations , Institute Of Drug Discovery At Leipzig University , Leipzig University , Epidemic Preparedness Innovations , Drug Discovery , Artificial Intelligence , Global Health Security , Disease X , Scientific Research , Science Amp Disease ,

HER3 gene mutations can worsen tumor growth in breast cancer, study suggests

HER3 gene mutations can worsen tumor growth in breast cancer, study suggests
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