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Robotics platform could revolutionize how labs track the spread of COVID-19, other pathogens


Robotics platform could revolutionize how labs track the spread of COVID-19, other pathogens
A robotics platform designed by Toronto researchers to screen thousands of COVID-19 samples at once has the potential to revolutionize how labs track the spread of viruses and other pathogens, according to new findings.
The study, out Wednesday in
Nature Communications, found that the next-generation, ultra-high-throughput sequencing platform, called C19-SPAR-Seq, designed by researchers from the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health, has a sensitivity rate greater than 95 per cent in positive cases during peak onset.
Identifying positive samples quickly and accurately is critical in beating this pandemic.With new and potentially dangerous variants now circulating, this is a platform that is scalable, automated and capable of analyzing thousands of COVID-19 patient samples in a single instrument run. ....

Laurence Pelletier , Tony Mazzulli , Jeff Wrana , Javier Hernandez , Emily Henderson , Ben Blencowe , Marie Ming Aynaud , Seda Barutcu , University Of Toronto , Department Of Molecular Genetics , University Health Network , Nature Communications , Sinai Health , Lunenfeld Tanenbaum Research Institute , Senior Investigator , Molecular Genetics , Mount Sinai Hospital , Seq System , High Throughput Sequencing , லாரன்ஸ் பெலெடீயர் , டோனி மஜ்ஜுழ்ளி , ஜேவியர் ஹெர்னாண்டஸ் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் டொராண்டோ , துறை ஆஃப் மூலக்கூறு ஜெநெடிக்ஸ் , பல்கலைக்கழகம் ஆரோக்கியம் வலைப்பின்னல் ,

Automated next generation sequencing platform can accurately screen thousands for COVID-19


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IMAGE: Jeff Wrana, left, is seen in this undated file photo at the Lunenfeld-Tanenbaum Research Institute in Toronto, Canada.
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Credit: Sinai Health
A robotics platform designed by Toronto researchers to screen thousands of COVID-19 samples at once has the potential to revolutionize how labs track the spread of viruses and other pathogens, according to new findings.
The study, out Wednesday in
Nature Communications, found that the next-generation, ultra-high-throughput sequencing platform, called C19-SPAR-Seq, designed by researchers from the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health, has a sensitivity rate greater than 95 per cent in positive cases during peak onset. ....

Marie Ming Aynaud , Laurence Pelletier , Ben Blencowe , Tony Mazzulli , Jeff Wrana , Javier Hernandez , Seda Barutcu , Department Of Molecular Genetics , University Health Network , Nature Communications , Lunenfeld Tanenbaum Research Institute , Krembil Foundation , University Of Toronto , Sinai Health , Action Initiative , Molecular Genetics , Mount Sinai Hospital , Seq System , Molecular Biology , Health Care , Medicine Health , Infectious Emerging Diseases , Robotry Artificial Intelligence , லாரன்ஸ் பெலெடீயர் , டோனி மஜ்ஜுழ்ளி , ஜேவியர் ஹெர்னாண்டஸ் ,