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In the jungle of artificial cells, these small factories to replicate the living

In the jungle of artificial cells, these small factories to replicate the living
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Alexandre oparineJean christophe baretUniversity of bordeauxPaul pascal research centerChristophe baret

Carbios Accelerates Its Enzyme Optimization With Screening Capabilities for Millions of Enzymes in a Day

Carbios has developed an ultra-high throughput microfluidic screening of PET-depolymerizing enzymes in partnership with the Paul Pascal Research Center1, a joint research unit of the CNRS2 and the

Clermont ferrandFrance generalKatel barretteAlexandre gillesAlexandra tauzinAnne henneckeMelissa flauraudMarie virginie kleinBenjamin audebertCarbios linkedinJean christophe baretCarbios instagramAlain martyPaul pascal research centreCentre de recherche paul pascalCentre national de la recherche scientifique

Expanding the boundaries of CO2 fixation

E-Mail IMAGE: Engineering of glycolyl-CoA carboxylase (GCC), the key enzyme of the TaCo pathway. GCC was developed on the scaffold of a naturally occurring propionyl-CoA carboxylase (WT). Rational design led to the. view more Credit: Max Planck Institute for Terrestrial Microbiology/Scheffen Photorespiration is a highly energy consuming process in plants that leads to the release of previously fixed CO2. Thus, engineering this metabolic process is a key approach for improvement of crop yield and for meeting the challenge of ever-rising CO2 levels in the atmosphere. Researchers led by Tobias Erb from the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, have now succeeded in engineering the TaCo pathway, a synthetic photorespiratory bypass. This new-to-nature metabolic connection opens up new possibilities of CO2 fixation and the production of value-added compounds.

Mecklenburg vorpommernMarieke scheffenJean christophe baretSandra schullerTobias erbMax planck institute of biochemistryFrench national centre for scientific researchGroup leader tobias erbMax planck instituteTerrestrial microbiologyArren bar evenMolecular plant physiologyFuture agricultureFrench national centreScientific researchGroup leader tobias