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Evolving Use of PARP Inhibitors Requires Biomarker-Driven Approaches to Treatment Selection in Prostate Cancer

Vivek K. Narayan, MD, MS, spotlights 3 case studies of patients with metastatic prostate cancer, delving into the influence of their unique mutational status on treatment decisions, scenarios in which to utilize PARP inhibitor monotherapy vs combination regimens, and key trials that support the use of each approach. ....

Fox Chase Cancer Center , United States , University Of Pennsylvania , Pooja Ghatalia , Jasone Shpilsky , Vivekk Narayan , Kevin Kayvan Zarrabi , Ronac Mamtani , Samuel Takvorian , Sidney Kimmel Cancer Center At Jefferson Health , Hospital Of The University Pennsylvania , Penn Medicine , Sidney Kimmel Cancer Center , Prostate Cancer ,