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What if You Knew Your Unique Risk for Every Disease?

“Polygenic risk scores” total hundreds or thousands of genetic factors to predict your risk of disease. A new study validates scores for AFib, diabetes, breast cancer, and more.

United statesBrigham biobankJason vassyAmerican heart associationAmerican college of cardiologyVeterans affairs boston healthcare systemHarvard medical schoolGenomic medicine at veterans affairs studyNature medicineMore definitiveAmerican collegeGenomic medicineVeterans affairs studyMass general brighamGenetic risk diseasesIseases and genetics

Genetic Test for Six Chronic Diseases Undergoing Clinical Trial

Researchers developed assays and supportive information to examine the expanded role of genetic information in patient care.

United statesUnited kingdomSamuel lambertJason vassyAmerican heart associationNational institute of diabetesUniversity of cambridge department public healthVeterans affairs boston healthcare systemUs department of veterans affairsNational health serviceBrigham laboratory for molecular medicineBaker systems genomics initiativeNational human genome research instituteDepartment of public healthBlood instituteNational heart

Researchers develop and validate polygenic risk scores for six common diseases

A person's risk of developing diseases such as type 2 diabetes or breast cancer may be influenced by thousands of genetic differences.

United statesMatthew leboJason vassyEmily hendersonBrigham laboratory for molecular medicineBrigham divisionBrigham precision population health at ariadne labsHarvard medical schoolVeterans affairs va boston healthcare systemNature medicineVeterans affairsBoston healthcare systemGeneral internal medicinePrimary carePrecision population healthAriadne labs

Newly developed genetic risk scores could help patients, physicians make health decisions

Newly developed genetic risk scores could help patients, physicians make health decisions
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United statesMatthew leboJason vassyAmerican heart associationNational institute of diabetesHarvard medical schoolBrigham laboratory for molecular medicineUs department of veterans affairsNational human genome research instituteBrigham precision population health at ariadne labsBrigham divisionNational heartBlood instituteVeterans affairs va boston healthcare systemNature medicineVeterans affairs