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Sosei Collaborates With GSK On Immune Disorders Of Digestive System; Eligible To Receive Up $481 Mln


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LONDON (dpa-AFX) - Japan s Sosei Group Corp said that it has reached a global collaboration and license agreement with GlaxoSmithKline Plc (GSK.L, GSK) targeting immune disorders of the digestive system in a deal worth up to $481 million.
Sosei said the agreement will focus on the discovery and development of selective, oral, small molecule agonists of GPR35, an important orphan G protein-coupled receptor (GPCR) with genetic association to inflammatory bowel disease (IBD) and other gastrointestinal immune disorders.
As per the deal, GSK licenses global rights to a portfolio of GPR35 agonists designed by Sosei Heptares using its StaR technology and structure-based drug design platform. The licensed portfolio includes an advanced lead preclinical compound as well as multiple differentiated back-up compounds. ....

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Sosei, GSK agree to develop inflammatory bowel disease treatment

Sosei, GSK agree to develop inflammatory bowel disease treatment
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