Janina Lewis News Today : Breaking News, Live Updates & Top Stories | Vimarsana

 E-Mail
IMAGE: This image shows expression of a specific ferroptosis marker called TfR1 in MYCN-amplified neuroblastoma tissues before and after treatment with auranofin, an FDA-approved drug for rheumatoid arthritis.
view more 
Credit: VCU Massey Cancer Center
Neuroblastoma is a cancer that develops in nerve tissue, most commonly in the glands around the kidneys. The gene MYCN is overexpressed in 20-25% of neuroblastoma, and MYCN-amplified neuroblastoma contributes to a considerable percentage of pediatric cancer-related deaths.
Anthony Faber, Ph.D., and a team of researchers at VCU Massey Cancer Center were awarded a grant from the American Cancer Society to study how MYCN and an abundance of iron can drive cancer cell death in neuroblastoma and potentially be targeted with novel treatments. This award is the first part of a potential two-stage grant worth a combined total of $600,000. ....

United States , Janina Lewis , Krista Powell , Sosipatros Boikos , Mayuri Shende , Sivapriya Ramamoorthy , Mikhail Dozmorov , Colin Coon , Richard Kurupi , Anthony Faber , Konstantinos Floros , Madhavi Puchalapalli , Johnr Congdon , Carter Fairchild , Jennifer Koblinski , School Of Medicine , Metabolon Inc , School Of Dentistry , Cancer Research , Mission Boost Grant , Phillips Institute For Oral Health Research , Philips Institute For Oral Health Research , Department Of Pathology , Massey Cancer Center , Pediatric Oncology Branch , American Cancer Society ,