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UVM gets $9 million to explore epigenetics of breast cancer | Vermont Business Magazine


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Larner College of Medicine faculty Gary and Janet Stein are principal investigators on a new $9 million grant from the National Cancer Institute to explore the epigenetics of breast cancer with the goal of finding new drug targets. (Photos: Sally McCay, Larner College of Medicine)
Project to Identify New Targets for Drug Treatment That Could Prevent or Halt Disease
Vermont Business Magazine A team of University of Vermont scientists and physician investigators at the UVM Cancer Center and the Northern New England Clinical and Translational Research Network has been awarded a $9 million, five-year grant from the National Cancer Institute (NCI) to investigate the underlying causes of breast cancer with the goal of identifying new cellular-level targets that could be treated with drugs to prevent the disease or halt its progression.  ....

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University Scholar Lecture Series – Gary S. Stein, Ph.D.


The Cancer-Compromised Genome
The Graduate College is pleased to present the Teams Live Event: The Cancer-Compromised Genome, a lecture by University Scholar Gary S. Stein, Ph.D. on Monday, March 22, 2021 at 4:30 pm. The event can be joined at http://go.uvm.edu/universityscholars.
A mechanistic and clinical challenge is understanding and treating cancer as a disease of compromised cellular and molecular organization. Cancer onset and progression are functionally associated with aberrant genetic (DNA-encoded) and epigenetic (non DNA-encoded) mechanisms that influence the transmission and retention of regulatory information during cell division. Cancer cells must sustain their compromised genome structure (deletions, amplifications, rearrangements), epigenetic status and function otherwise cancer would be cured by cell division. Each regulatory component of gene expression is linked to architectural organization of regulatory machinery in the cell nucleus. Fidelity of ....

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Detailed text transcripts for TV channel - FOXNEWS - 20131013:10:35:00

Ending up outside. he walked to a neighborhood a mile away and found himself a family. we think he s a wonderful dog. as much as i would love for his owner to come and claim him, i can t wait to welcome him into my family. the human society is waiting one more day to make sure his original owners don t claim him. let s get outside to janet stein. she whiggled her way out of the studio. we have good things coming. it is still dark out here. a lot of people are coming home from their nightly activities in the bars. i remember those days. yes. let s take a look at what we re dealing with. we have the pesky low. that will move thankfully finally today. that will be the end of your wet weather as we head into the new work week. look at the potential for flooding across texas. ....

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Detailed text transcripts for TV channel - FOXNEWS - 20130929:11:37:00

okay, go! [ bleep ]. you let the dog go. the dog. that s a good one. the kid takes a spill, the dog takes over. the pint size dog stealing the sled as soon as the kid falls off. no word on when this video was shot, it s just beginning to go viral. is it already snowing out there? janet said it is snowing up in the cascade mountains of washington. maybe oregon. you are correct, mike. you are correct. yes. you win a prize. please save me dunkin donuts. which one do you want? all of them, please. two boxes. remember that saturday night live sketch where i don t know who it was, but they were eating mini donuts for breakfast. it was a little ....

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Detailed text transcripts for TV channel - FOXNEWS - 20130929:11:10:00

A soldier gets creative with a surprise for his family disguising himself as the high school polar bear mascot. the army specialist never saw it coming. he had no idea what was going on for a few seconds. it was amazing. they had no idea i was out here in that uniform or anything. specialist justin may was gone for 11 months including 9 months that he spent in afghanistan. his father knew he was back in america but had no idea he d arrive in their hometown. they re getting creative. getting better and better. one guy dressed up in a football uniform yesterday. i was here walking down manhattan. there s guys dressed in elmo costum costumes. you never know. you never know. dressed up as janet stein, you never know. hey, janice. good morning. let s take a look at what s going on outside especially the northwest. look at all of the moisture streaming into the northwest. ....

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