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This prostate disease drug may help lower risk of Parkinson's disease


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In a new study, researchers found that taking a particular type of medication to treat an enlarged prostate is linked to a reduced risk of Parkinson’s disease.
The findings provide compelling evidence that
terazosin, and similar medications, might have the potential to prevent or delay the development of Parkinson’s disease.
The research was conducted by a team at the University of Iowa.
In the study, the team used data on almost 300,000 older men from two large, independent patient datasets.
They examined whether taking terazosin is associated with the development of Parkinson’s disease.
The findings build on previous preclinical research by the team, which showed that terazosin enhances cellular energy levels and can prevent or slow the progression of Parkinson’s disease in animal models. ....

University Of Iowa , Jacob Simmering , பல்கலைக்கழகம் ஆஃப் ஐயுவா , ஜாகோப் வேகவைக்கிறது ,

Parkinson's Disease Risk Potentially Lowered by Prostate Drug


Roughly 10 million individuals worldwide have Parkinson’s disease (PD), and unfortunately, that number continues to grow as the population ages. There is no cure for PD, but medications can help control symptoms, often dramatically. Now, according to a large observational study led by scientists at the University of Iowa (UI), with colleagues in Denmark and China, taking a particular type of medication to treat enlarged prostate is associated with a reduced risk of developing Parkinson’s disease.
Their findings are published in
“A treatment that prevents or delays development of PD is a critical unmet need. Terazosin and closely related drugs were recently discovered to enhance glycolysis and reduce PD progression in animal models and human clinical databases,” the researchers wrote. ....

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