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Research reveals mechanical hearts can regenerate some heart tissue

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for ....

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Signal from fat cells associated with heart

Signal from fat cells associated with heart
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Distress signal from fat cells prompts heart to shore up defences against consequences of obesity

Distress signal from fat cells prompts heart to shore up defences against consequences of obesity
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United States , Christym Gliniak , Shujuan Li , Christinem Kusminski , Jan Bernd Funcke , Ruth Gordillo , Philippe Scherer , Nolwenn Joffin , Heshama Sadek , Dmitri Samovski , Clair Crewe , Samuel Klein , Pamela Fischer Posovszky , Alexandral Ghaben , Shiuhwei Chen , Yucel Akgul , J Fred Schoellkopf Jr , National Academy Of Sciences , Ulm University Medical Center , University Of Texas Southwestern Medical Center , Diabetes Research , Washington University School Of Medicine , Howard Hughes Medical Institute Investigators , National Academy Of Medicine , Texas Southwestern Medical Center , Cell Metabolism ,

Three longtime antibiotics could offer alternative to addictive opioid pain relievers

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IMAGE: This illustration shows the atomic level resolution of the tetracycline antibiotic bound to the EphB1 receptor.
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Credit: UT Southwestern Medical Center
DALLAS - Feb. 22, 2021 - Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in
PNAS, could offer an alternative to opioid-based painkillers, addictive prescription medications that are responsible for an epidemic of abuse in the U.S.
Over 100 million Americans are affected by chronic pain, and a quarter of these experience pain on a daily basis, a burden that costs an estimated $600 billion in lost wages and medical expenses each year. For many of these patients - those with cancer, diabetes, or trauma, for example - their pain is neuropathic, meaning it s caused by damage to pain-sensing nerves. ....

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