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Researchers uncover new clues about links between parent age and congenital disorders medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.
Research Reveals Parent Age's Impact on Congenital Disorders miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
<p>A new paper in <em>Genome Biology and Evolution</em> finds that the link between paternal age and rare congenital disorders is more complex than scientists had previously thought. While researchers have long realized that older fathers are more likely to have children with bone and heart malformations, such as Achondroplasia, Apert, or Noonan syndrome, or neurodevelopmental disorders, schizophrenia, and autism, new examination indicates that while the link between some pathogenic mutations increases with paternal age, others do not and may even occur in the father’s testis before sexual maturity.</p> ....
Both young and old fathers carry gene variants associated with congenital disorders in children, which have so far been linked with delayed fatherhood, new research has found. ....
Our cells carry two copies of each chromosome, one inherited from each parent. Meiosis is a key biological process that reduces the number of the chromosomes to compensate for a doubling that occurs during fertilization, when the paternal (sperm) and ....