Stem cell therapy can repair brain damage and improve memory function in mice
A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia, a new UCLA study finds.
Dementia can arise from multiple conditions, and it is characterized by an array of symptoms including problems with memory, attention, communication and physical coordination. The two most common causes of dementia are Alzheimer s disease and white matter strokes -; small strokes that accumulate in the connecting areas of the brain. It s a vicious cycle: The two leading causes of dementia are almost always seen together and each one accelerates the other, said Dr. S. Thomas Carmichael, senior author of the study and interim director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.
UCLA Broad Stem Cell Research Center/Science Translational Medicine
Microscope images showing brain tissue that has been damaged by white matter stroke (left) and then repaired by the new glial cell therapy (right). Tiare Dunlap |
April 21, 2021
A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia, a new UCLA study finds.
Dementia can arise from multiple conditions, and it is characterized by an array of symptoms including problems with memory, attention, communication and physical coordination. The two most common causes of dementia are Alzheimer’s disease and white matter strokes small strokes that accumulate in the connecting areas of the brain.