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Men and women experience disease differently. Yet it has always been assumed that the results from ‘pre-clinical’ research on males apply to females too. ....
The assumption that women are just smaller versions of men has been widely used in biomedical research. A new mouse study indicates that’s unlikely to be true. ....
A new study in mice has shown that the biomedical assumption that women are "smaller males" is not well supported for most clinical traits, and adverse drug reactions are unlikely to be alleviated by simply adjusting for body weight. ....