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Oral IL-23 Inhibitor Calms Moderate to Severe Psoriasis

The small-molecule oral investigational agent JNJ-77242113 at the highest dose tested was associated with reductions in psoriasis severity comparable to injectable biologic agents. ....

New York , United States , University Of Pennsylvania , Markg Lebwohl , Joelm Gelfand , Robert Bissonnette , Icahn School Of Medicine At Mount Sinai , Department Of Dermatology At Mount Sinai Medicine , Innovaderm Research , Psoriasis Area , Severity Index , New England Journal , Medscape Medical News , Clinical Therapeutics , Icahn School , Mount Sinai , Mount Sinai Medicine , Dermatology Clinical Studies Unit , Global Assessment , Biologic Therapy , Plaque Psoriasis , Light Therapy , Covid 19 , 019 Novel Coronavirus , 019 Ncov , Uhan Coronavirus ,

Expert Highlights Biologics in the Pipeline for Eczema

Dr David Rosmarin reviewed several biologics in clinical trials that target interleukin-4 and other receptors. ....

Keymed Biosciences , David Rosmarin , European Academy Of Dermatology , Indiana University , Revolutionizing Atopic Dermatitis , Eczema Area , Severity Index , Investigator Global Assessment , Biologic Therapy , Atopic Dermatitis , Atopic Eczema , Monoclonal Antibody , Healthcare And Medical Technology , Ealth And Medical Tech , Ealth And Med Tech , Ealth And Medical Technology , Healthcare Technology , Medical Technology , Clinical Research , Clinical Trials , Linical Studies , Pre Clinical Trial ,

Experimental Topical Drug Shows Promise for AD, Psoriasis

In the phase 2 study, researchers at 34 sites in four countries randomized 104 patients with mild to moderate AD or psoriasis to receive the topical PDE4 inhibitor or a vehicle once daily for 6 weeks. ....

San Diego , United States , Lawrencef Eichenfield , University Of California , Eczema Area , Severity Index , Psoriasis Area , Plaque Psoriasis , Atopic Dermatitis , Atopic Eczema , Severity Indices , Wound Management , Wound Care , Board Certification , Oard Recertification , Biologic Therapy , Diarrhea Diarrhoea , Pain Management ,

Artificial Sweeteners Alter the Duodenal Microbiome

Nonsugar sweeteners affected the stool and small bowel microbiomes differently, and the type of sweetener consumed proved relevant to which microbiome changes occurred. ....

United States , Los Angeles , Ava Hosseini , Entire Intestinal Microbiota , Neuroendocrine Ecosystem , Biologic Therapy , Social Determinants Of Health , Social Determinants Of Health Sdoh , Genomics Genomic Medicine , Body Mass Index , Alignant Neoplasia , Alignant Neoplasm , Klebsiella Infection , Match Day , Watch Application ,

How Does Lebrikizumab Perform Across Different Subgroups?

Key eligibility criteria for both trials included adults or adolescents with a diagnosis of AD as defined by the AAD consensus criteria, for at least 1 year prior to screening. ....

United States , Northwestern University , Eli Lilly , Raj Chovatiya , American Academy Of Dermatology Consensus Criteria , Revolutionizing Atopic Dermatitis , American Academy , Dermatology Consensus Criteria , Global Assessment , Eczema Area , Severity Index , Pruritus Numeric Rating Scale , African American , Atopic Dermatitis , Atopic Eczema , Biologic Therapy ,