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UNIFI Long-Term Extension Shows Safety, Efficacy of Ustekinumab for Ulcerative Colitis Through 4 Years

Results confirmed the long-term efficacy of ustekinumab maintenance in patients with ulcerative colitis, demonstrating consistent rates of symptomatic remission and endoscopic improvement with no new safety signals. ....

Waqqas Afif , Media Center , Drug Administration , Mcgill University , Inflammatory Bowel Disease Questionnaire , Ulcerative Colitis Through , Final Results , Severely Active Ulcerative , Maintenance Ustekinumab , Ulcerative Colitis , Interleukin 23 , Il 23 , Il 12 , Inflammatory Bowel Disease , Crohn X27s Disease ,

Case Reports Support Use of IL-23 Inhibitors to Treat Psoriasis in Cancer Setting

Authors describe 3 patients with cancer who were given interleukin-23 (IL-23) inhibitors for psoriasis or immune-related psoriasis. ....

Princess Margaret Cancer Centre , Medical Case , Interleukin 23 , Il 23 , Brain Metastasis , Active Cancer Setting , Braf Mutated ,

Mirikizumab induces clinical remission in patients with ulcerative colitis

1. In this randomized controlled trial, patients with ulcerative colitis taking mirikizumab had higher rates of clinical remission compared to those taking a placebo. 2. Opportunistic infections occurred more frequently in the mirikizumab group. Evidence Rating Level: 1 (Excellent) Study Rundown: Recent clinical trials and approval of monoclonal antibody treatments for ulcerative colitis suggest interleukin-23 ....

Minute Medicine Inc , Rating Level , Confidence Interval , Chronic Disease , Infectious Disease , Interleukin 23 , Opportunistic Infections , Ulcerative Colitis ,