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Transcenta Continues to Push the Boundary of Cell Culture Productivity by Achieving > 6 g/L PER Day Volumetric Productivity in Continuous Perfusion Platform News provided by Share this article Share this article SUZHOU and HANGZHOU, China, March 16, 2021 /PRNewswire/ Transcenta, a global biotherapeutics company with fully-integrated capabilities in discovery, development and manufacturing of antibody-based therapeutics, today announced a major breakthrough in its continuous perfusion cell culture platform by achieving volumetric productivity of > 6 g/L per day while maintaining process and product quality attributes in a state of control for a 4-week culture. This productivity improvement represents a 15-fold increase in drug substance output per year when compared to same cell line in conventional fed-batch process (6 g/L over 14 days). At such high productivity, one 100L or 1,000L single use bioreactor can produce approximately 130 kg or 1.3 metric tons of total drug substanc

United statesPrnewswire transcentaChris hwangClinical development centersTranscenta holdingMerck kgaMerck kgaaProduct development centerTranslational research centerChief technology officerIntegrated continuous bioprocessingDarmstadt germanyManufacturing facilityExternal partnering centerTranscenta holding limitedஒன்றுபட்டது மாநிலங்களில்