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1. In this randomized controlled trial, insulin icodec demonstrated superior HbA1c reduction as compared to once-daily basal insulin analogs in insulin-naïve type two diabetes (T2D). 2. Insulin icodec showed improved treatment satisfaction and compliance as compared to once-daily basal insulin analogs in insulin naïve T2D. Evidence Rating Level: 1 (Excellent) Study Rundown: Two prior phase ....
1. Mean HbA1c reduction at 26 weeks was comparable in the weekly icodec and daily degludec groups. 2. The risk of hypoglycemia was significantly higher among patients taking weekly insulin icodec compared to those taking daily insulin degludec. Evidence Rating Level: 1 (Excellent) Study Rundown: First-line therapy for type 1 diabetes includes a combination of ....
In this randomized controlled trial, weekly insulin icodec use resulted in better glycemic control than daily insulin glargine in patients with type two diabetes. Once-weekly insulin icodec also resulted in a greater reduction in glycated hemoglobin levels than once-daily insulin glargine. Evidence Rating Level: 1 (Excellent) Study Rundown: Current treatment for type two diabetes includes initiation of once ....